Infants born weighing less than 2500 grams (5 pounds and 8 ounces) are at increased risk of serious health problems including risk of death before the first birthday. In 1990, 7.4% of babies born in Florida weighed less than 2500 grams. This reached a high of 8.8% in 2008 and has remained near that proportion. In 2020, 8.71% of births were low birthweight and in 2021, the proportion rose to 9.0%.

Infants born before completing 37 weeks of gestation are classified as preterm births. These infants are at greater risk of health and developmental problems including increased risk of death before their first birthday. In 1990, 8.5% of births inFlorida were preterm. This percentage rose to 10.3% in 2000, peaked in 2005 at 11.2% and has remained in the 10-11% range since. In 2020, 10.5% and in 2021, 10.9% of births were preterm.

Medicaid was the payment source for delivery for 48.8% of Florida's births in 2010. In 2020, the proportion decreased to 46.8%, and in 2021, to 45.5%

Since 1990, the proportion of Florida's deliveries that are C-Section increased. In 1990,25.5% of births were delivered by C-Section. This proportion dropped to 21.9% in 1995 but rose again to 25.5% in 2000, increasing to 37.8% in 2010 and to 35.9% in 2020. In 2021, 35.7% of births were delivered by C-Section.